moprevention Meets Glucose Control
نویسنده
چکیده
wnloade report by Memmott et al. (beginning on page 1066 in this issue of the journal) assessing the efficacy antidiabetes drug metformin in a mouse model of lung carcinogenesis suggests protective effects via ossible avenues: Decreased circulating insulin and insulin-like growth factor levels and energy stress g to inhibition of mammalian target of rapamycin signaling. These potential mechanisms are disleadin cussed in this perspective, as are their implications for cancer prevention and therapy. Cancer Prev Res; 3(9); 1049–52. ©2010 AACR.
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